At The London Cosmetic Clinic, we offer a range of systemic therapies for abnormal pigmentation which include oral carotenoids, glutathione, melatonin, polypodium leucotomos, tranexamic acid, hydrophilic extract and procyanidin, which have all been proven to appear safe for oral use.
Yes, tranexamic acid can treat existing pigmentation effectively and are recommended for preventing post-inflammatory pigmentation. It is a safe and efficacious treatment for melasma refractory to topical skin-lightening agents. It has been found to lighten hyperpigmentation by inhibiting the synthesis of melanin (skin pigment) and the transfer of pigment to the topmost layer of the skin. It also mitigates the UV radiation–induced pigmentation response.
Overall, the patients tolerated adjuvant oral tranexamic acid therapy well, and improvement occurred, typically, after two months. Nearly 90 percent–89.7 percent of patients–documented melasma improvement.
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